Mike Easterling, Constella Health Services

A PBPK model for a mixture of dioxin-like chemicals.

A PBPK model for dioxin (TCDD) was used as the framework for models of 
TCDD, PCB126, PeCDF, and a mixture of these three chemicals. A goal was to 
assess how a model developed specifically for TCDD would serve as a 
general Ah receptor model for other dioxin-like chemicals as well as a 
mixture of dioxin-like chemicals.  I'll discuss the latest work on the 
model.