Mathematical Model of Cytomegalovirus Infection

Grace M. Kepler
Center for Research in Scientific Computation
North Carolina State University

HCMV infection is a significant health threat to immunosuppressed patients. Patient health outcome could be improved with suitable mathematical modeling that could predict the disease course in individuals and one that could suggest optimized treatment strategies. We illustrate our approach to within-patient modeling and prediction with similar HIV-1 modeling work by this group. We then present an initial model for HCMV infection in healthy and immunosuppressed patients and show how this model can begin to provide a window into the dynamics of HCMV infection in transplant patients.

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