Mathematical Model of Cytomegalovirus Infection
Grace M. Kepler
Center for Research in Scientific Computation
North Carolina State University
HCMV infection is a significant health threat to immunosuppressed
patients. Patient health outcome could be improved with suitable
mathematical modeling that could predict the disease course in
individuals and one that could suggest optimized treatment
strategies. We illustrate our approach to within-patient modeling and
prediction with similar HIV-1 modeling work by this group. We then
present an initial model for HCMV infection in healthy and
immunosuppressed patients and show how this model can begin to provide
a window into the dynamics of HCMV infection in transplant patients.
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