Featured Research:
RNA in Biopolymer Nanostructures
Dr. Yara Yingling
and her group in materials science explore biopolymeric
and composite nanoassembly processes.
The NCSU Blade Center enables Dr. Yingling to perform
complex simulations to guide
efforts in synthesis and to analyze properties of biopolymers.
For example, RNA based biopolymers can be used
as nanoarrays and nanocircuits. Dr. Yingling proposes to use
protein-free RNA nanoparticles as efficient
minimally toxic drug delivery devices.
Dr. Yingling and her team
designed an RNA hexagonal nanoring formed from
six simple building blocks held together via loop-loop
contacts. Drugs or therapeutic agents can be incorporated
within or attached to the ends of building blocks. Moreover,
the 3' and 5' sequence can be engineered to facilitate a
self-assembly of these rings into a nanotube.
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