Sandra Siegel, Ph.D

Curriculum Vitae

Education:

2005 – present             North Carolina State University, College of Veterinary Medicine (Raleigh, NC)
                                    D.V.M. Student

2003                           University of North Dakota (Grand Forks, ND)
                                    Doctoral Degree
                                    Anatomy and Cell Biology (focus: Neuroscience)

Dissertation title: "Characterization of src-suppressed c kinase substrate (SSeCKS) immunolabeling in rat primary sensory neurons"

1997                            State University of New York at Stony Brook (Stony Brook, NY)
                                    Bachelor of Science
                                    Major:  Psychology;  Minor:  Philosophy

Publications:

Peer-reviewed journal articles

Siegel, S.M., Lee, J.W., Chang, Y., Oaklander, A.L.  Minimal distal nerve injuries suffice to model complex regional pain syndrome-I.  Under review: Anesthesiology.

Oaklander, A.L. and Siegel, S.M.  Cutaneous innervation:  Form and function.  Journal of AmericanAcademy of Dermatology, 2005;53:1027-37.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS-immunolabeling in the rat primary sensory neurons, Brain Research Feb. 1, 2002; 926: 126-36.

Siegel, S.M. and Carr, P.A. The plasticity of SSeCKS-immunolabeling in rat primary sensory neurons. Under review Brain Research: Development.

Abstracts

Siegel, S.M., Lee, J.W., Zheng, L., Oaklander, A.L. Micro distal nerve injury (MDNI) of rat tibial nerve by needlestick causes hyperalgesia, motor changes, and pathologic changes consistent with CRPS American Pain Society Annual Meeting, Boston, MA 2005.                                                                

Lee, J.W., Siegel, S.M., Zheng, L., Oaklander, A.L. Minimal distal nerve injury (MDNI): correlation between development of pain behavior and cellular markers in spinal dorsal horn American Pain Society Annual Meeting, Boston, MA  2005.

Siegel, S.M., Lee, J.W., Tellez, I., Zheng, L., Horowitz, S.H., Oaklander, A.L. Minimal distal injury (MDI) by needle injury to rat tibial nerve causes hyperalgesia and pathologic changes consistent with CRPS. Soc. Neurosci. Abstr., Program No. 982.10, Washington, DC: Society for Neuroscience, 2004.

J.W. Lee, S.M. Siegel, L. Zheng, I. Tellez, A.L. Oaklander. Hyperalgesia from minimal distal injury (MDI) to tibial nerve: Correlation of behavior and pathology in spinal cord and sciatic nerve. Soc. Neurosci. Abstr., Program No. 298.4. Washington, DC: Society for Neuroscience, 2004.

L. Zheng, J.W. Lee, S.M. Siegel, A.L. Oaklander. Effect of lesion size on loss of PGP9.5-ir paw innervation contralateral to one-sided nerve injuries. Soc. Neurosci. Abstr., Program No. 982.9, Washington, DC: Society for Neuroscience, 2004.

C.P. Irmen, S.M. Siegel, A. Campbell, R. Reilkoff, P.A. Carr. Neurotrophic factor and adrenergic receptor labeling in SSeCKS. Soc. Neurosci. Abstr., Program No. 289.16. Washington, DC: Society for Neuroscience, 2004.

Siegel, S.M. Development of a rat model of CRPS-I based on partial injury to nociceptive neurons- Final report. Reflex Sympathetic Dystrophy Syndrome Association Review, Vol. 17 (2), 2004.  http://www.rsds.org/3/research/rsdsa_funded_research.html

Siegel, S.M. Weatherly, J.N., and Carr, P.A. A developmental profile of SSeCKS immunolabeling in rat primary sensory neurons. Soc. Neurosci. Abstr., Program No. 382.13, Washington, DC: Society for Neuroscience, 2003.

Siegel, S.M., Weatherly, J.N., Carr, P.A. A developmental profile of SSeCKS immunolabeling in primary sensory neurons of the rat. 23rd Annual Frank Low Research Day, page 37, 2003.

Siegel, S.M. and Carr, P.A. A developmental profile of SSeCKS immunolabeling in primary sensory neurons of the rat. Proceedings of the 95th AnnualNorth DakotaAcademy of Science Meeting, Vol 57, 2003.

Siegel, S.M. and Carr, P.A. Plasticity of SSeCKS-immunolabeling in rat primary sensory neurons. Soc. Neurosci. Abstr., Vol. 28, Washington, DC: Society for Neuroscience, 2002.

Siegel, S.M. and Carr, P.A. The plasticity of SSeCKS-immunolabeling in rat primary sensory neurons. 22nd Annual Frank Low Research Day, page 50, 2002.

Siegel, S.M., Grove, B.D. and Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons. Soc. Neurosci. Abstr., Vol. 27, Program No. 816.12, 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons.  17th Annual University of Manitoba and University of North Dakota Anatomy Interchange, September 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons. University of North Dakota Basic Sciences Retreat, October 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. Localization of SSeCKS immunolabeling within rat primary sensory neurons. 21st Annual Frank Low Research Day, April 2001 p.37. 

Siegel, S.M., Grove, B.D. and Carr, P.A. SSeCKS-immunolabeling in the rat nervous system. 20th Annual Frank Low Research Day, April 2000.

Siegel, S.M., Grove, B.M., and Carr, P.A. SSeCKS-immunolabeling in the rat nervous tissue. University of North Dakota Basic Sciences Retreat, October 2000.

Siegel, S.M., Grove, B.M., and Carr, P.A. SSeCKS-immunolabeling in the rat nervous tissue. 16th Annual University of Manitoba and University of North Dakota Anatomy Interchange, September 2000.

Carr, P.A., Liu, M., Siegel, S.M., Zaruba, R. Enzyme histochemical profile of immunohistochemically identified Renshaw cells in rat lumbar spinal cord. Soc. Neurosci. Abstr., Vol. 26, pt.1, p. 694, 2000.

Siegel, S.M. Interference of automatic auditory identification with visual stimuli. State University of New York at Stony Brook Psychology Research Conference; April 28, 1996.

Senior Project:
Siegel, S.M. Effects of encoding and objective decision on memory experience. Senior Project, State University of New York at Stony Brook, May 1996.

Seminars, Invited Speaker:

Siegel, S.M. and Fink, E.  Complex Regional Pain Syndrome (CRPS):  Approaches in Clinical Practice and Advancements in Research (Parts II & III).  Neuroscience Meeting, Anesthesia Department.  Massachusetts General Hospital, Boston, MA. February 17 & March 17, 2005.

Siegel, S.M. and Fink, E.  CRPS: Clinical and research updates.  Department of Orthopedics, Brown University, Providence R.I. February 2, 2005.

Siegel, S.M. The developing neuron: SSeCKS marks the spot. Anatomy & Cell Biology Departmental Seminar, February 24, 2003.

Siegel, S.M. and Carr, P.A. The characterization of SSeCKS immunolabeling in rat primary sensory neurons.  Basic Sciences Retreat, October 2002. 

Siegel, S.M. and Carr, P.A. The plasticity of SSeCKS-immunolabeling in rat primary sensory neurons.  University of Manitoba/University of North Dakota 18th Annual Anatomy Interchange, September 2002. 

Siegel, S.M. The plasticity of SSeCKS-immunolabeling in rat primary sensory neurons.  Anatomy & Cell Biology Departmental Seminar, February 25, 2002

Siegel, S.M. Immunolabeling of SSeCKS in the rat nervous tissue.  Anatomy & Cell Biology Departmental Seminar, December 4, 2000.

Abstracts Presented:

Siegel, S.M., Lee, J.W., Zheng, L., Oaklander, A.L. Micro distal nerve injury (MDNI) of rat tibial nerve by needlestick causes hyperalgesia, motor changes, and pathologic changes consistent with CRPS. Pain 6(3), Suppl. 1 (2005):S13.
                                                                       
Lee, J.W., Siegel, S.M., Zheng, L., Oaklander, A.L. Minimal distal nerve injury (MDNI): correlation between development of pain behavior and cellular markers in spinal dorsal horn Pain 6(3), Suppl. 1 (2005):S12.

L. Zheng, J.W. Lee, S.M. Siegel, A.L. Oaklander. Effect of lesion size on loss of PGP9.5-IR paw innervation contralateral to one-sided nerve injuries. Soc. Neurosci. Abstr., Program No. 982.9, 2004.

Siegel, S.M., Lee, J.W., Tellez, I., Zheng, L., Horowitz, S.H., Oaklander, A.L. Minimal distal injury (MDI) by needle injury to rat tibial nerve causes hyperalgesia and pathologic changes consistent with CRPS. Soc. Neurosci. Abstr., Program No. 982.1, 2004.

Siegel, S.M., Weatherly, J.N., Carr, P.A. A developmental profile of SSeCKS immunolabeling in primary sensory neurons of the rat. Soc. Neurosci. Abstr., Program No. 382.13, 2003.

Siegel, S.M., Weatherly, J.N., Carr, P.A. A developmental profile of SSeCKS immunolabeling in primary sensory neurons of the rat. 23rd Annual Frank Low Research Day, April, 2003.

Siegel, S.M. and Carr, P.A. A developmental profile of SSeCKS immunolabeling in primary sensory neurons of the rat. North Dakota Academy of Science, March 2003.

Siegel, S.M. and Carr, P.A. Plasticity of SSeCKS-immunolabeling in rat primary sensory neurons. Soc. Neurosci. Abstr., Vol. 28, 2002.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons.  17th Annual University of Manitoba and University of North Dakota Anatomy Interchange, September 2001.

Siegel, S.M. and Carr, P.A. The plasticity of SSeCKS-immunolabeling in rat primary sensory neurons. 22nd Annual Frank Low Research Day, April, 2002.

Siegel, S.M., Grove, B.D. and Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons. Soc. Neurosci. Abst., Vol. 27, Program No. 816.12, 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons.  17th Annual University of Manitoba and University of North Dakota Anatomy Interchange, September 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. SSeCKS immunolabeling in rat primary sensory neurons. University of North Dakota Basic Sciences Retreat, October 2001.

Siegel, S.M., Grove, B.D., Carr, P.A. Localization of SSeCKS immunolabeling within rat primary sensory neurons. 21th Annual Frank Low Research Day, April 200. 

Siegel, S.M., Grove, B.D. and Carr, P.A. SSeCKS-immunolabeling in the rat nervous system. 20th Annual Frank Low Research Day, April 2000.

Siegel, S.M., Grove, B.M., and Carr, P.A. SSeCKS-immunolabeling in the rat nervous tissue. University of North Dakota Basic Sciences Retreat, October 2000.

Siegel, S.M., Grove, B.M., and Carr, P.A. SSeCKS-immunolabeling in the rat nervous tissue. Annual University of Manitoba and University of North Dakota Anatomy Interchange (poster presentation), September 2000.

Siegel, S.M. Interference of automatic auditory identification with visual stimuli. State University of New York at Stony Brook Psychology Research Conference; April 28, 1996

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NC State College of Veterinary Medicine
Comparative Pain Research Laboratory
4700 Hillsborough Street
Raleigh, NC 27606