College of Veterinary Medicine

With a $1 million grant from the National Institutes of Health to find cancer-associated genes in man’s best friend, Dr. Matthew Breen, a College of Veterinary Medicine professor of genomics, hopes findings will lead to a cause and cure for non-Hodgkins lymphoma in both dogs and humans. Having participated in the successful nationwide dog genome sequencing project, Breen says the dog genome is very similar to the human genome. Since dogs and humans share the same environment, their cancers occur under the same circumstances and have the same characteristics. “If we can pinpoint the cancer genes in dogs, where it’s much easier to find them, then we know where to start looking for them in people,” says Breen. He has already started identifying aberrant regions in the dog genome and hopes to have the cancer-associated genetic candidates identified in dogs within the next few years.

College Awards 10-Year Comparison 1998-2007

Dr. Gregg Dean, professor of immunopathology, has been named the first director of the recently established Center for Comparative Medicine and Translational Research (CCMTR) in the College of Veterinary Medicine. Since many of the diseases and medical conditions that affect animals also affect humans, the CCMTR enhances collaborative, translational and interdisciplinary approaches for comparative studies. Its One Medicine concept encourages sharing new discoveries among more than 100 faculty in 16 departments in four colleges to improve health care for all species. Dean’s research, for example, involves the development of novel vaccine strategies for the prevention of human and feline immunodeficiency virus infection (HIV/FIV).

 

Dr. Matthew Breen

Dr. Gregg Dean