The CQSB offers several opportunities for pre- and post-doctoral training.
CQSB Graduate Fellows
- A limited number of research positions for NCSU pre-doctoral students in the quantitative sciences are available. These CQSB Graduate Fellows gain exposure to the interdisciplinary approach promoted by the Center through participation in CQSB research projects. Information on our current Fellows is available on the Personnel page.
Curriculum in Modeling and Simulation in Drug Development
- The US Food and Drug Administration, through its Critical Path Initiative and more generally, has highlighted the urgent need to bring new technologies to bear on the development of new pharmaceutical and biologic entities. A key strategy that has been embraced by both the agency and industry is the integration of quantitative modeling of biological systems, including representations of pharmacokinetics, pharmacodynamics, and disease progression, with statistical modeling of population behavior as a foundation for investigating the potential efficacy and effectiveness of new entities in the development pipeline and for designing clinical confirmatory studies. This modeling and simulation enterprise requires investigators who have been trained at the interface of mathematics, statistics, and biology. However, there is a dearth of new graduates with such interdisciplinary training.
- A key initiative of the CQSB is to develop a novel curriculum that
seeks to provide a foundation to students in the quantitative sciences
in the area of Modeling and Simulation in Drug Development. The
current vision is that doctoral students in statistics, applied
mathematics, biomathematics, and other quantitative disciplines could
follow a "concentration" in this area in which some of their elective
courses are chosen from a series of targeted courses. The CQSB is
currently seeking input from advisors at Merck, Eli Lilly, and other
companies on the development of the curriculum, including specific